STING agonist-8 dihydrochloride

STING Agonist-8 Dihydrochloride (Compound 5-AB) is a potent small molecule activator of the STING pathway, demonstrating high potency with an EC50 of 27 nM in human THP1-Dual KI-hSTING-R232 reporter cells. This agonist is a valuable research tool for studying innate immune responses and STING-dependent signaling in both cellular and animal models of oncology and immunotherapy.