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Sulfo-PDBA-DM4

SKU: orb1987703

Description

Sulfo-PDBA-DM4 is a glutathione-cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs). It enables the targeted delivery of the cytotoxic maytansinoid DM4, a potent tubulin inhibitor, for research in oncology, supporting both in vitro and in vivo ADC efficacy studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1461704-01-7
MW978.58
FormulaC42H60ClN3O15S3
SMILES[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(C\C(C)=C/C=C/[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCC(C(O)=O)S(O)(=O)=O |c:17,t:19|
TargetPROTAC Linker,Drug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information