Surfen dihydrochloride

SKU: orb1701546

Description

Surfen dihydrochloride is a heparan sulfate antagonist that neutralizes the anticoagulant effects of heparin and LMWH. It has demonstrated research utility in studying viral entry mechanisms, such as semen-mediated HIV infection, and in inhibiting specific bacterial toxins and coagulation factors in vitro.

Research Area

Cardiovascular Research, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	5424-37-3
MW	445.35
Purity	97.08%
Formula	C₂₁H₂₂Cl₂N₆O
SMILES	Cl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1
Target	Antibiotic,HSV,VEGFR,FGFR,Antiviral
Solubility	H2O:5 mg/mL (11.23 mM)

Bioactivity

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Target IC50	FGFR2:5 μM

Storage & Handling

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Storage	keep away from moisture,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Surfen, NSC-12155, FGF2, Antiviral, Antibiotic, Aminoquinuride, Aminoquinuride 2HCl, Aminoquinuride dihydrochloride, Aminokinuride, Aminokinuride 2HCl, Aminokinuride dihydrochloride

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Compound Identifiers

PubChem CID

79472 ↗

Key Properties

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No computed properties available.

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