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Taprenepag

SKU: orb1304459

Description

Taprenepag (CP-544326) is a potent and selective EP2 prostaglandin receptor agonist with an EC50 of 2.8 nM. It has been investigated in clinical trials for lowering intraocular pressure in ocular hypertension and open-angle glaucoma, supported by both in vitro receptor studies and in vivo pharmacological research.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number752187-80-7
MW478.52
Purity98.89% (May vary between batches)
FormulaC24H22N4O5S
SMILESOC(=O)COc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)c1
TargetProstaglandin Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.18 mM);DMSO:55 mg/mL (114.94 mM)

Bioactivity

Target IC50
Prostaglandin E2:2.8 nM(EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

cells, CP544326, CP-544326, CP 544326, cAMP, inhibit, intraocular, Inhibitor, levels, HEK293, Prostaglandin Receptor, ProstaglandinReceptor, pressure, PGE2, Taprenepag

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 70.00
5 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 110.00
10 mg
$ 140.00
25 mg
$ 240.00
50 mg
$ 370.00
100 mg
$ 520.00
200 mg
$ 710.00
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