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Tat-IKIP (46-60)

SKU: orb3142589

Description

Tat-IKIP (46-60) is a transmembrane peptide that targets IκB kinase (IKK). It inhibits the activation of IKK and the expression of NF-κB target genes by disrupting the IKKβ/NEMO complex. In mouse models, Tat-IKIP (46-60) significantly alleviates DSS-induced acute inflammation in inflammatory bowel disease (IBD) and reduces zymosan-induced acute arthritis in acute arthritis models (AAM). This compound is applicable in research on inflammatory diseases such as IBD, pancreatitis, and rheumatoid arthritis.

Images & Validation

Key Properties

TargetNF-κB,IκB/IKK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Tat-IKIP (46-60) (orb3142589)

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