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TD114-2

SKU: orb2564366

Description

TD114-2 (compound 29) is a potent, selective GSK-3β inhibitor (IC50 = 48 nM) with selectivity conferred by a key interaction with ARG141. It is a valuable research tool for studying GSK-3β's role in diabetes and neurodegenerative disease models, applicable in both in vitro and in vivo experimental settings.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number436866-52-3
MW529.58
FormulaC30H31N3O6
SMILESO=C1NC(=O)C=2C3=CN(C=4C=CC=CC34)CCOCCOCCOCCOCCN5C=C(C=6C=CC=CC65)C12
TargetGSK-3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information