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Teniposide

SKU: orb1308336

Description

Teniposide (VM-26) is a podophyllotoxin-derived chemotherapeutic agent that acts as a topoisomerase II inhibitor, stabilizing the enzyme-DNA complex to block DNA replication. It is widely used in cancer research, demonstrating activity in both in vitro cytotoxicity assays and in vivo models of leukemia and solid tumors.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number29767-20-2
MW656.65
Purity97.84% (May vary between batches)
FormulaC32H32O13S
SMILESO=C1[C@@]2([C@@H](C=3C([C@@H](O[C@@H]4O[C@]5([C@]([C@H](O)[C@H]4O)(O[C@@H](OC5)C6=CC=CS6)[H])[H])[C@]2(CO1)[H])=CC7=C(C3)OCO7)C8=CC(OC)=C(O)C(OC)=C8)[H]
TargetTopoisomerase
SolubilityDMSO:125 mg/mL (190.36 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.05 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NSC 122819, inhibit, NSC122819, NSC-122819, Inhibitor, Topoisomerase, Topo II, Teniposide, VM26, VM-26, VM 26

Similar Products

  • Teniposide [orb1225406]

    >98% (HPLC)

    29767-20-2

    656.66

    C32H32O13S

    25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 100.00
50 mg
$ 130.00
100 mg
$ 190.00
200 mg
$ 280.00
DispatchUsually dispatched within 5-10 working days
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