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Terbutaline Sulfate

SKU: orb1308089

Description

Terbutaline Sulfate

Research Area

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number23031-32-5
MW274.32
Purity99.47% (May vary between batches)
FormulaC12H19NO3·1/2H2SO4
SMILESOS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c1cc(O)cc(O)c1
TargetAdrenergic Receptor,Antibacterial,Antibiotic
SolubilityDMSO:50 mg/mL (182.27 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (3.65 mM);H2O:100 mg/mL (364.54 mM)

Bioactivity

Target IC50
β2-adrenoceptor:53 nM
In Vivo
In all BChE variants, Terbutaline exhibits reversible competitive inhibition, with dissociation constants (Kd) of 0.18 mM for UU, 0.31 mM for FF, and 3.3 mM for AA homozygotes. Additionally, Terbutaline facilitates bronchodilation by selectively targeting β2-adrenergic receptors.
In Vitro
Terbutaline acts on the β2 receptors in the bronchial, vascular, and uterine smooth muscles, stimulating them. It also exerts an effect on uterine smooth muscles by inhibiting contractions.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Terbutaline, Terbutaline Hemisulfate, Terbutaline hemisulfate, Terbutaline Sulfate, β2-adrenergic receptor, Inhibitor, inhibit, J774 macrophages, MPK-1, macrophages, Beta Receptor, Adrenergic Receptor, AdrenergicReceptor, adrenergic receptor agonist, Antibiotic, asthma, Bacterial

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Key Properties

No computed properties available.

Protocol Information

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500 mg
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