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TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

SKU: orb3174847

Description

TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). It consists of a topoisomerase 1 (topoisomerase1) inhibitor known as Topi MF-6 and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala). This compound is used for the synthesis of ADCs.

Images & Validation

Key Properties

CAS Number2857037-73-9
MW717.79
FormulaC36H39N5O9S
SMILESN(C([C@@H](NC([C@@H](NC(CS)=O)[C@H](C)C)=O)C)=O)C12CC(C1)(C2)C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=CC8=C(C7)OCO8
TargetDrug-Linker Conjugates for ADC,Topoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information