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Thalidomide-5-NH2-CH2-COOH

SKU: orb1303326

Description

Compound 114 (Thalidomide-5-NH2-CH2-COOH) is a bifunctional molecule acting as a selective protomyosin receptor kinase inhibitor and an E3 ligase ligand. It serves as a chemical probe for targeted protein degradation studies in oncology and neurological disease research, applicable in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2412056-27-8
MW331.28
Purity95.95% (May vary between batches)
FormulaC15H13N3O6
SMILESO=C1N(C(=O)C=2C1=CC(NCC(O)=O)=CC2)C3C(=O)NC(=O)CC3
TargetOthers
SolubilityDMSO:3.32 mg/mL (10.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.02 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, E3 ligase, E3 ligase-recruiting Moiety, neurodegenerative, inhibit, inflammatory, infectious, Ligands for E3 Ligase, cancer, selective, tropomyosin receptor kinase, trk, Thalidomide5NH2CH2COOH, Thalidomide-5-NH-2-CH2-COOH, Thalidomide-5-NH2-CH2-COOH, Thalidomide 5 NH2 CH2 COOH, Thalidomide
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 90.00
5 mg
$ 140.00
10 mg
$ 180.00
25 mg
$ 280.00
50 mg
$ 440.00
100 mg
$ 620.00
DispatchUsually dispatched within 5-10 working days
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