Cart summary

You have no items in your shopping cart.

THR-β agonist 6

SKU: orb1982622

Description

THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH).

Images & Validation

Key Properties

CAS Number2791290-58-7
MW457.27
FormulaC20H14Cl2N6O3
SMILESClC1=C(N2C3=C(C=C2)N(C(C)C)C(=O)C=C3)C(Cl)=CC(=C1)N4N=C(C#N)C(=O)NC4=O
TargetOthers,Thyroid hormone receptor(THR)

Storage & Handling

Storage-20°C
DisclaimerFor research use only

Similar Products

  • ALG-055009 [orb2665105]

    2542029-03-6

    425.23

    C16H14Cl2N6O4

    25 mg, 100 mg, 50 mg
  • MGL-3196 [orb1223645]

    >98% (HPLC)

    920509-32-6

    435.2

    C17H12Cl2N6O4

    1 g, 500 mg, 25 mg, 50 mg, 100 mg, 2 mg, 5 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

THR-β agonist 6 (orb1982622)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%