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THR-β agonist 6

SKU: orb1982622

Description

THR-β Agonist 6 is a potent, orally bioavailable, and selective thyroid hormone receptor beta agonist, demonstrating a high liver-to-serum distribution ratio. Its selectivity profile and favorable pharmacokinetics support its use in research models of liver diseases, including nonalcoholic steatohepatitis (NASH).

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2791290-58-7
MW457.27
FormulaC20H14Cl2N6O3
SMILESClC1=C(N2C3=C(C=C2)N(C(C)C)C(=O)C=C3)C(Cl)=CC(=C1)N4N=C(C#N)C(=O)NC4=O
TargetOthers,Thyroid hormone receptor(THR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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THR-β agonist 6 (orb1982622)

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