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TLR7/8 agonist 9

SKU: orb1944361

Description

Compound 25a is a potent dual TLR7/8 agonist with EC50 values of 40 nM (hTLR7) and 23 nM (hTLR8). It exhibits anti-tumor activity and can synergize with PD-1/PD-L1 blockade in cancer immunotherapy research, as supported by studies in both cellular assays and animal models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2649170-17-0
MW366.46
FormulaC20H26N6O
SMILESN(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1
TargetTLR,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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TLR7/8 agonist 9 (orb1944361)

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