Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

TNF,Others Antibody

SKU: orb3031975

Description

NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4). Its Fc region contains three point mutations (S239D/A330L/I332E; DLE) to enhance binding to CD16a (FcγRIIIa), leading to increased antibody-dependent cellular cytotoxicity (ADCC). By binding to tumor-expressed B7-H4, NC762 inhibits tumor growth in vivo. This compound can be utilized in research on advanced or metastatic solid tumors.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetOthers,TNF
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

Free Secondary Antibody (20 ul)0/0

Please add an antibody product to your cart first.