TNF,Others Antibody

SKU: orb3031975

Description

NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4). Its Fc region contains three point mutations (S239D/A330L/I332E; DLE) to enhance binding to CD16a (FcγRIIIa), leading to increased antibody-dependent cellular cytotoxicity (ADCC). By binding to tumor-expressed B7-H4, NC762 inhibits tumor growth in vivo. This compound can be utilized in research on advanced or metastatic solid tumors.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	Others,TNF
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Others,TNF

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