Toll-Like Receptor 2 Rabbit mAb

SKU: orb1565339

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Description

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response

Research Area

Immunology & Inflammation

Images & Validation

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Item 1 of 3

Tested Applications	ICC, IF, IHC-Fr, IHC-P, WB
Dilution range	WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Reactivity	Mouse

Key Properties

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Antibody Type	Primary Antibody
Clonality	Monoclonal
Isotype	IgG
Clone No.	R06-8B6
Immunogen	Recombinant protein of mouse TLR2
Target	Tlr2
Molecular Weight	Calculated MW: 89 kDa
Purity	Affinity Purified
Purification	Affinity Purified
Conjugation	Unconjugated

Storage & Handling

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Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles
Form/Appearance	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
Buffer/Preservatives	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.
Concentration	0.3 mg/ml
Disclaimer	For research use only

Alternative Names

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Toll-Like Receptor 2; TLR2; CD282; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4

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Immunohistochemistry analysis of paraffin-embedded mouse lung using Toll Like Receptor 2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of TLR2 in Raw264.7 lysates using TLR2 antibody.

Immunocytochemistry analysis of TLR2 (green) in Raw264.7 using TLR2 antibody, and DAPI (blue).

Quick Database Links

Gene Symbol

Tlr2

UniProt

Q9QUN7

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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IHC-P

Immunohistochemistry Paraffin

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IHC-Fr

Immunohistochemistry Frozen

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Immunofluorescence

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ICC

Immunocytochemistry

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