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TRPM5 agonist-1

SKU: orb3173745

Description

TRPM5 agonist-1 is an orally active TRPM5 agonist with a pEC50 value of 8.1. It displays excellent selectivity for related cation channels (TRPM8, TRPV1, TRPV4, TRPA1, TRPM4) with selectivity greater than 100-fold. TRPM5 agonist-1 induces local stimulation of gastrointestinal transit in mice and is useful for studying the promotion of gastric motility.

Images & Validation

Key Properties

CAS Number2768029-03-2
MW316.22
FormulaC11H7Cl2N3S2
SMILESClC=1SC(=NC1)CNC2=CC=3SN=CC3C=C2Cl
TargetTRP/TRPV Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information