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Tryptanthrin

SKU: orb1299508

Description

Tryptanthrin is a natural product that acts as a DNA gyrase inhibitor. It is used in biochemical research to study bacterial replication and has shown antibacterial activity in both in vitro assays and in vivo infection models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number13220-57-0
MW248.24
Purity>98%
FormulaC15H8N2O2
SMILESO=C1N2C(C(=O)C=3C2=CC=CC3)=NC=4C1=CC=CC4
TargetTryptophan
SolubilitySoluble in DMSO (up to 30 mg/ml)

Bioactivity

Target IC50
Leukotriene (human whole blood):10 µM (IC50)
In Vivo
Tryptanthrin suppresses angiogenesis in vivo
In Vitro
Tryptanthrin blocks signaling through VEGFR2 at the level of ERK1/2 signaling in vitro

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NSC 349447; Couroupitine A

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Key Properties

No computed properties available.

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Tryptanthrin (orb1299508)

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5 mg
¥ 2,340.00
25 mg
¥ 4,550.00
DispatchUsually dispatched within 3-5 working days
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