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TUL01101

SKU: orb1744208

Description

TUL01101 is a potent, selective, and orally bioavailable JAK1 inhibitor (IC50 = 3 nM). It demonstrates efficacy in in vivo models of autoimmune inflammation and is a key research tool for studying rheumatoid arthritis and related JAK-STAT signaling pathways.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2411222-97-2
MW429.46
FormulaC22H25F2N5O2
SMILESC(=O)(N1CC2(C1)CCC(CC2)C=3N4C(=NC(NC(=O)C5CC5)=N4)C=CC3)[C@H]6C(F)(F)C6
TargetJAK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • (Rac)-TUL01101 [orb3135245]

    2411222-71-2

    429.46

    C22H25F2N5O2

    50 mg, 10 mg
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Key Properties

No computed properties available.

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Protocol Information

TUL01101 (orb1744208)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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