Turbinaric acid

SKU: orb1707788

Description

Turbinaric acid is a cytotoxic squalene-derived carboxylic acid isolated from the brown alga Turbinaria ornata. It serves as a research tool for studying cytotoxic mechanisms in vitro and has been investigated in fields such as natural products chemistry and marine pharmacology.

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Key Properties

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CAS Number	56882-00-9
MW	400.64
Purity	99.62% (May vary between batches)
Formula	C₂₇H₄₄O₂
SMILES	CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC(O)=O
Target	Others

Bioactivity

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In Vitro

Methods: Peripheral blood mononuclear cells containing NK cells were isolated and cocultured with target K562 cells at three different effector-to-target (E:T) ratios of 50:1, 25:1, and 12.5:1. Prednisolone hemisuccinate or IVIG were then added to the tubes at an E:T ratio of 50:1 to assess the inhibitory effect. Percent killing was recorded and statistically analyzed using the Student t test. Results: In experiments with an E:T ratio of 50:1 and either Prednisolone hemisuccinate or IVIG in the coculture, the mean target cell killing rate was 26.4%. In cultures using the same E:T ratio, this killing rate was significantly reduced in the presence of IVIG (9.9%) or Prednisolone hemisuccinate (13.6%) (P < 0.001 for both analyses). Prednisolone hemisuccinate was able to inhibit the cytolytic activity of NK cells.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Turbinaric acid

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Compound Identifiers

PubChem CID

6438506 ↗

Key Properties

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No computed properties available.

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Turbinaric acid

Description

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

Quality Guarantee

Compound Identifiers

Key Properties

Documents Download

Request a Document

Protocol Information

Turbinaric acid (orb1707788)

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