Tuspetinib hydrate

SKU: orb2565107

Description

Tuspetinib hydrate is a potent, orally available, and selective type I FLT3 inhibitor with low nM IC₅₀ values against FLT3 WT, ITD, and D835Y mutants. It disrupts key signaling pathways (e.g., STAT5, ERK) and has demonstrated activity in inhibiting proliferation and inducing apoptosis in FLT3-mutant leukemia cells in preclinical studies.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2758339-04-5
MW	519.08
Formula	C₂₉H₃₅ClN₆O
SMILES	ClC=1C(C=2C=3C(NC2)=CC(C)=CC3)=NC(NC4=CC(=CC(CN5C[C@@H](C)N[C@@H](C)C5)=C4)C6CC6)=NC1.O
Target	Apoptosis,FLT

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

135390909 ↗

Key Properties

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No computed properties available.

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