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TYK2-IN-11

SKU: orb1688378

Description

TYK2-IN-11 (Compound 5B) is a highly potent and selective Tyk-2 inhibitor, exhibiting IC50 values of 0.016 nM against TYK2-JH2 and 0.31 nM against JAK1-JH2. This small molecule is a valuable research tool for investigating JAK/STAT signaling pathways in the context of autoimmune and inflammatory disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2757009-40-6
MW383.42
FormulaC18H17N5O3S
SMILESN(C=1C(=CN=C(NC(C)=O)C1)C2=CC=CC=N2)C=3N=C(S(C)(=O)=O)C=CC3
TargetJAK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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