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Tyk2-IN-15

SKU: orb2565105

Description

Tyk2-IN-15 (Compound 97) is a potent and selective Tyk2 inhibitor, demonstrating an IC50 of ≤10 nM against the Tyk2-JH2 pseudokinase domain. This tool compound is used in preclinical research to investigate signaling pathways in autoimmune and inflammatory disease models, both in cellular and animal studies.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number3010873-44-3
MW429.47
FormulaC21H25F2N7O
SMILESN(C(C)=O)C=1C=C2N(N=C(C2=CN1)N3C[C@@H](N(C)C)CC3)C=4N=C(C(C)(F)F)C=CC4
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information