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Tyk2-IN-18

SKU: orb2564664

Description

Tyk2-IN-18 (compound 86) is a highly potent small molecule inhibitor of Tyrosine Kinase 2 (Tyk2), demonstrating an IC50 of <10 nM against the JAK2-JH2 pseudokinase domain. This inhibitor is a valuable research tool for investigating JAK/STAT signaling in autoimmune and inflammatory disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number3024860-29-2
MW418.44
FormulaC21H24F2N4O3
SMILESO=C(NC1=NC=C2C(=C1)N(C=3N=C(C=C(OCCOC)C3)C(F)(F)C)CC24CC4)C
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Tyk2-IN-18 (orb2564664)

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