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Tyk2-IN-3

SKU: orb1708307

Description

Tyk2-IN-3 is a potent and selective small molecule inhibitor targeting the Tyk2 pseudokinase domain with an IC50 of 485 nM. It serves as a valuable chemical probe for investigating JAK-STAT signaling in immunological and inflammatory disease research, applicable in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1779493-12-7
MW520.63
FormulaC25H24N6O3S2
SMILESCN1C=2C3=C(SC(=N3)C4=CC([C@H](NC(=O)C5=C(S(C)(=O)=O)C=CC=C5)C)=CC=C4)N=C(NC)C2N=C1
TargetJAK,Tyrosine Kinases

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information