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UKH-1114

SKU: orb2814483

Description

UKH-1114 is a potent and selective σ2 receptor/Tmem97 agonist (Ki = 46 nM) with demonstrated antinociceptive efficacy. It effectively reverses nerve injury-induced mechanical hypersensitivity in murine models without motor deficits, making it a valuable research tool for investigating neuropathic pain mechanisms in both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2113664-14-3
MW375.43
FormulaC22H24F3NO
SMILESFC(F)(F)C1=CC=C(C=C1)C=2C=CC3=C(C2)C4N(CCCO)CCCC3C4
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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UKH-1114 (orb2814483)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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