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Upadacitinib tartrate

SKU: orb1685483

Description

Upadacitinib is a potent, selective JAK1 inhibitor with approximately 74-fold selectivity over JAK2 in cellular cytokine assays. It has demonstrated efficacy in rat models of arthritis and is widely used in research on autoimmune and inflammatory diseases, including in vitro mechanistic studies and in vivo preclinical models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1607431-21-9
MW602.521
FormulaC21H33F3N6O11
SMILESO.O.O.O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@@H]1CN(C[C@@H]1c1cnc2cnc3[nH]ccc3n12)C(=O)NCC(F)(F)F
TargetJAK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Upadacitinib tartrate (orb1685483)

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