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Val-Ala-PABC-Exatecan trifluoroacetate

SKU: orb2283474

Description

Val-Ala-PABC-Exatecan trifluoroacetate is a cleavable Tesirine linker-drug conjugate for constructing antibody-drug conjugates (ADCs). It incorporates the potent topoisomerase I inhibitor Exatecan, enabling targeted drug delivery for the research and development of novel anticancer therapeutics in both in vitro and in vivo studies.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2928571-45-1
MW868.83
FormulaC42H44F4N6O10
SMILESC(C(O)=O)(F)(F)F.N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
TargetTopoisomerase,Drug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information