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Varenicline-d4

SKU: orb3138637

Description

Varenicline-d4 is a deuterium-labeled form of Varenicline. Varenicline (CP 526555) acts as a partial agonist of the α4β2 nAChR nicotinic acetylcholine receptor, with an EC50 of 2.3 μM. It is a full agonist for the α3β4 nAChR and α7 nAChR acetylcholine receptors, with EC50 values of 55 μM and 18 μM, respectively. As a nicotine ligand based on the cytisine structure, Varenicline shows potential for use in smoking cessation research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2183239-01-0
MW215.29
FormulaC13H13N3
SMILESC1=2C(C3CC1C(NC3([2H])[2H])([2H])[2H])=CC=4C(C2)=NC=CN4
TargetAChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Varenicline-d4 (orb3138637)

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