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VLX 1500

SKU: orb3172813

Description

VLX 1500 is a potent deubiquitinating enzyme (DUBs) inhibitor designed to overcome resistance to traditional proteasome inhibitors. It triggers ER stress-mediated apoptosis by specifically blocking USP14/UCHL5 activity on the 19S regulatory particle, leading to a lethal accumulation of ubiquitinated proteins, widely used in drug target screening for relapsed hematological malignancies.

Images & Validation

Key Properties

CAS Number330450-45-8
MW419.39
FormulaC22H17N3O6
SMILESO=C(N1CC(C(C(C1)=CC2=CC=C([N+]([O-])=O)C=C2)=O)=CC3=CC=C([N+]([O-])=O)C=C3)C=C
TargetDUB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 170.00
DispatchUsually dispatched within 5-10 working days
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