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VRK1/CK1-IN-1

SKU: orb3134371

Description

VRK1/CK1-IN-1 (compound 36) is a dual inhibitor targeting vaccinia-related kinase 1 (VRK1) and casein kinase 1 (CK1), with a Ki of 37.9 nM for VRK1. It exhibits IC50 values of 17 nM and 15 nM for CK1 δ and ε isoforms, respectively.

Research Area

Metabolism Research, Neuroscience, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number3050772-20-5
MW416.38
FormulaC19H18F2N6O3
SMILESC(N1C=2C(=NC(NC3=CC(F)=C(O)C(F)=C3)=NC2)N(C)[C@@H](C)C1=O)C=4ON=C(C)C4
TargetCasein Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information