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VSP-77

SKU: orb3173628

Description

VSP-77 is an orally active PPARγ agonist. It selectively enhances the expression of insulin sensitivity-related genes (Glut4 and Adiponectin) by inhibiting CDK5-mediated phosphorylation of PPARγ at Ser-273. In a high-fat diet-induced diabetic mouse model, VSP-77 significantly improves glucose tolerance and reduces fasting blood glucose and insulin levels. VSP-77 is applicable for diabetes research.

Images & Validation

Key Properties

CAS Number1854008-12-0
MW298.81
FormulaC16H23ClO3
SMILESO=C(O)COC(C1=CC=C(Cl)C=C1)CCCCCCC
TargetPPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information