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VU0119498

SKU: orb1299108

Description

VU0119498 is a selective M1 muscarinic receptor agonist (EC50 = 3.1 μM) and a positive allosteric modulator for M3 and M5 receptors. It exhibits neuroprotective properties and is utilized in research exploring cholinergic signaling, cognitive function, and neurodegenerative disease models in both cellular and animal studies.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number79183-37-2
MW316.15
Purity97.56% (May vary between batches)
FormulaC15H10BrNO2
SMILESBrc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1
TargetAChR
SolubilityDMSO:15 mg/mL (47.45 mM)

Bioactivity

Target IC50
M1:3.1 μM(EC50)
In Vivo
VU0119498 treatment of wild-type mice caused a significant increase in plasma insulin levels, accompanied by a striking improvement in glucose tolerance

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

VU0119498, VU-0119498, VU 0119498, inhibit, Muscarinic acetylcholine receptor, pan, mAChR, Inhibitor, antidiabetic
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
25 mg
$ 80.00
50 mg
$ 100.00
100 mg
$ 130.00
200 mg
$ 170.00
DispatchUsually dispatched within 3-5 working days
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