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WEE1-IN-10

SKU: orb2664172

Description

WEE1-IN-10 (compound 77) is a potent Wee1 kinase inhibitor with an IC50 of 0.524 µM against LOVO cell growth. It is a valuable research tool for studying Wee1-dependent cancers, including pancreatic cancer, melanoma, and glioma, in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number2226938-19-6
MW565.5
Purity98.18%
FormulaC28H30Cl2N8O
SMILESO=C1N(C=2N(C=3C1=CN=C(NC4=CC(C)=C(C=C4)N5C[C@H](C)N(C)[C@H](C)C5)N3)CCN2)C6=C(Cl)C=CC=C6Cl
TargetWee1

Bioactivity

Target IC50
Wee1 (LOVO cells):0.524 μM
In Vitro
WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor that effectively suppresses the growth of LOVO cells, with an IC₅₀ of 0.524 μM. WEE1-IN-10 is a valuable compound for studying diseases linked to dysregulated Wee1 activity.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

WEE1-IN-10 (orb2664172)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
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% Tween 80 +
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1 mg
¥ 1,560.00
5 mg
¥ 3,510.00
10 mg
¥ 4,680.00
25 mg
¥ 7,670.00
50 mg
¥ 11,180.00
DispatchUsually dispatched within 5-10 working days
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