Xanomeline oxalate

SKU: orb1708212

Description

Xanomeline oxalate

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	141064-23-5
MW	371.45
Purity	99.10%
Formula	C₁₆H₂₅N₃O₅S
SMILES	OC(=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1
Target	AChR
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.38 mM);DMSO:45 mg/mL (121.15 mM)

Bioactivity

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In Vivo	Xanomeline robustly stimulates in vivo PI hydrolysis, an effect blocked by muscarinic antagonists, indicating mediation by muscarinic receptors. In mice, the ED100 for Xanomeline-induced stimulation of [3H]-IP accumulation in the hippocampus is 54 μmole/kg, while in rats, it is 8.1 μmole/kg in the hippocampus. Read more...
In Vitro	Xanomeline stimulates phosphoinositide (PI) hydrolysis in A9 L m1 cells and inhibits [3H]-PZ and [3H]-OXO-M binding to rat brain, with Kis of 7 and 3 nM, respectively. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Xanomeline Oxalate, muscarinic receptor, LY 246708 Oxalate, LY246708 oxalate, LY246708 Oxalate, LY-246708 Oxalate

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Compound Identifiers

PubChem CID

18920248 ↗

Key Properties

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No computed properties available.

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