Xanomeline tartrate

SKU: orb1691631

Description

Xanomeline tartrate (LY 246708 tartrate) is a selective M1/M4 muscarinic acetylcholine receptor agonist. It exhibits antipsychotic and pro-cognitive effects in preclinical models, supporting its research application in neuropsychiatric disorders such as schizophrenia and Alzheimer's disease.

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	152854-19-8
MW	431.5
Purity	99.99% (May vary between batches)
Formula	C₁₈H₂₉N₃O₇S
SMILES	O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1
Target	AChR,Others
Solubility	DMSO:247.5 mg/mL (573.58 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.59 mM)

Bioactivity

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In Vivo	In Male Cebus apella monkeys, Xanomeline tartrate ( 0.5-3 mg / kg ; s.c. ; 1-3 hours ) can induce salivation and vomiting in some monkeys.
In Vitro	Xanomeline tartrate (LY 246708) (0.1-10 μM; CNS4U) shows an overall increase in average firing rate, indicating the functional presence of M1 receptors in hiPSC-derived neurons. Read more...

Storage & Handling

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Storage	keep away from direct sunlight,keep away from moisture,store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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LY 246708 tartrate, LY246708 tartrate, LY-246708 tartrate

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Compound Identifiers

PubChem CID

162640440 ↗

Key Properties

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No computed properties available.

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