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XRCC4 (N) Antibody, Rabbit Polyclonal

SKU: orb107118

Description

Rabbit polyclonal to XRCC4. DNA repair protein XRCC4 is involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. XRCC4 binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Research Area

Epigenetics & Chromatin

Images & Validation

Tested ApplicationsIP, WB
ReactivityHuman, Mouse

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenN-terminal region of human XRCC4
Molecular Weight38
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti DNA repair protein XRCC4 antibody, anti X-ray repair cross-complementing protein 4 antibody
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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
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IP
Immunoprecipitation
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Available Sizes

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100 μl
$ 540.00
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Free Secondary Antibody (20 ul)0/0

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