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XRD-0394

SKU: orb2565042

Description

XRD-0394 is a potent, selective, and orally bioavailable dual inhibitor of ATM and DNA-PKcs. It synergistically enhances the cytotoxic effects of ionizing radiation in tumor models and improves the activity of PARP and topoisomerase I inhibitors in cellular studies, supporting its investigation in DNA damage response and cancer therapy research.

Research Area

Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2595308-10-2
MW527.61
FormulaC26H30FN5O4S
SMILESO=C1C2(C=3C=4C(N=CC3N1C)=CC(F)=C(C4)C=5C=C(NS(C)(=O)=O)C(OCCNC(C)C)=NC5)CCC2
TargetDNA-PK,ATM/ATR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

XRD-0394 (orb2565042)

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