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YD-3

SKU: orb2814728

Description

YD-3 is a PAR4 antagonist that inhibits thrombin-induced platelet aggregation (IC₅₀=28.3 µM in rabbits) and VSMC proliferation via Ras/ERK pathways, reducing neointimal thickening in vivo. It suppresses thrombin-induced Flk-1 expression and is a useful tool for studying thrombin-driven angiogenesis and vascular remodeling.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number170632-41-4
MW356.42
FormulaC23H20N2O2
SMILESO=C(OCC)C=1C=CC(=CC1)C2=NN(C=3C=CC=CC23)CC=4C=CC=CC4
TargetThrombin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 5-10 working days
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