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YJZ5118

SKU: orb3028811

Description

YJZ5118 is a CDK12/13 inhibitor, possessing IC50 values of 39.5 nM and 26.4 nM for CDK12 and CDK13, respectively. This compound can inhibit tumor cell proliferation by inducing DNA damage and apoptosis (Apoptosis) and exhibits a synergistic effect with Akt inhibitors. YJZ5118 is applicable in cancer research.

Images & Validation

Key Properties

CAS Number3031861-18-1
MW620.787
FormulaC36H44N8O2
SMILESN(C(NCC1=CC=CC=C1)=O)(C2=CC(NC(C=C)=O)=C(C=C2)N3CCC(N(C)C)CC3)[C@@H]4CC[C@@H](NC5=CC=C(C#N)C=N5)CC4
TargetCDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

YJZ5118 (orb3028811)

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