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Yoda2

SKU: orb3136068

Description

Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM). Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

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Yoda2

Key Properties

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CAS Number3081450-95-2
MW435.39
FormulaC16H9Cl2KN2O2S2
SMILESO=C(C1=CC=C(C2=NN=C(SCC3=C(Cl)C=CC=C3Cl)S2)C=C1)[O-].[K+]
TargetNO Synthase,Piezo Channel

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quick Database Links

Gene Symbol
NO Synthase,Piezo Channel

Protocol Information

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
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