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(Z)-4-Hydroxytamoxifen

SKU: orb1224264

Description

A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium; shows a 100-fold increased affinity for ER and approximately 100-times more potent than trans-tamoxifen in suppressing cell growth and plasminogen activator activity.

Images & Validation

Key Properties

CAS Number68047-06-3
MW387.5139
Purity>98% (HPLC)
FormulaC26H29NO2
SMILESOC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1
TargetEstrogen Receptor/ERR
SolubilityDMSO: ≥ 28 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

trans-4-Hydroxytamoxifen

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Protocol Information

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200 mg
500 mg
5 mg
$ 120.00
10 mg
$ 160.00
25 mg
$ 320.00
50 mg
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100 mg
$ 890.00