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(Z)-RG-13022

SKU: orb2283705

Description

(Z)-RG-13022 is a selective EGFR tyrosine kinase inhibitor with an IC50 of 11 µM for DNA synthesis in HN5 cells, demonstrating threefold greater potency than its (E)-isomer. This compound is used in breast cancer research to study EGFR-driven cell proliferation in vitro.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number149286-90-8
MW266.29
FormulaC16H14N2O2
SMILESC(=C(\C#N)/C=1C=CC=NC1)\C2=CC(OC)=C(OC)C=C2
TargetOthers,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 180.00
10 mg
$ 290.00
50 mg
$ 1,030.00
DispatchUsually dispatched within 5-10 working days
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