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Z-VAE(OMe)-fmk

SKU: orb1737894

Description

Z-VAE(OMe)-fmk is a cell-permeable, irreversible inhibitor of UCHL1 that uniquely binds to the enzyme's P1' site, mimicking the proposed binding mode of an endogenous substrate's C-terminal extension. This compound is a valuable chemical tool for probing UCHL1 function in neurodegenerative disease models and ubiquitin-proteasome system research both in vitro and in vivo.

Images & Validation

Key Properties

CAS Number1027141-02-1
MW481.51
FormulaC23H32FN3O7
SMILES[C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@@H](C)C)=O)C)=O)(CCC(OC)=O)C(CF)=O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information