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Zemprocitinib

SKU: orb2564631

Description

Zemprocitinib (Compound 1) is a potent and selective JAK1 inhibitor, demonstrating IC50 values of 5.95 nM for JAK1, 141.3 nM for JAK2, and 119 nM for TYK2. This small molecule is a valuable research tool for investigating JAK-STAT signaling in both cellular assays and preclinical models of immune-mediated diseases.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

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Key Properties

CAS Number2417414-44-7
MW345.42
FormulaC16H19N5O2S
SMILESO=S(=O)(NC12CC(N3C=NC4=CNC5=NC=CC5=C43)(C1)C2)CCC
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Zemprocitinib (orb2564631)

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