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ZG-10

SKU: orb1986987

Description

ZG-10 (JNK-IN-2) is a pan-JNK inhibitor that effectively blocks JNK1, JNK2, and JNK3 isoforms. It has been utilized in research to investigate the mechanisms of SARS-CoV-2 infection, including studies on virus-induced cellular stress and apoptosis pathways in vitro.

Research Area

Infectious Disease & Virology, Signal Transduction

Images & Validation

Key Properties

CAS Number1408077-04-2
MW493.57
FormulaC28H27N7O2
SMILESO=C(C1=CC=C(NC(/C=C/CN(C)C)=O)C=C1)NC2=CC(NC3=NC(C4=CC=CN=C4)=CC=N3)=CC=C2
TargetOthers

Bioactivity

Target IC50
JNK3:709 nM|JNK2:1140 nM|JNK1:809 nM
In Vitro
ZG-10 is a JNK inhibitor with IC50 values of 809 nM, 1140 nM, and 709 nM for JNK1, JNK2, and JNK3, respectively.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ZG 10, ZG10, ZG-10, JNK-IN-2
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information