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ZK 216348

SKU: orb3132257

Description

ZK 216348 is a non-steroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to progesterone receptors and mineralocorticoid receptors with IC₅₀ values of 20.4 nM and 79.9 nM, respectively, and may be useful for studying inflammatory bowel disease (IBD).

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number669073-68-1
MW476.45
Purity99.93% (May vary between batches)
FormulaC24H23F3N2O5
SMILESC(CC(C(NC=1C=C2C(=CC1)C(=O)ON=C2C)=O)(C(F)(F)F)O)(C)(C)C3=C4C(CCO4)=CC=C3
TargetProgesterone Receptor,Glucocorticoid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information