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12(S)-HHT

SKU: orb2893604

Description

12(S)-HHT is an endogenous cyclooxygenase-derived metabolite of arachidonic acid and a BLT2 receptor agonist. It supports epithelial homeostasis and modulates inflammation, notably by upregulating MKP-1 to suppress the p38 MAPK/NF-κB pathway and IL-6 production, as demonstrated in UVB-irradiated HaCaT keratinocyte studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number54397-84-1
MW280.4
Purity98.45%
FormulaC17H28O3
SMILES[C@@H](/C=C/C=C/C/C=C\CCCC(O)=O)(CCCCC)O
TargetEndogenous Metabolite,Leukotriene Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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12(S)-HHT (orb2893604)

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250 μg
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¥ 6,110.00
100 μg
¥ 20,800.00