3-Bromopyruvic acid

SKU: orb1301412

Description

3-Bromopyruvic acid (3-BP) is a potent hexokinase II inhibitor with a Ki of 2.4 mM, disrupting glycolytic energy metabolism in tumor cells. It has demonstrated antitumor activity in vitro and in vivo and can act as a chemopotentiator for platinum-based chemotherapeutics in cancer research.

Research Area

Cell Biology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	1113-59-3
MW	166.96
Purity	99.64% (May vary between batches)
Formula	C₃H₃BrO₃
SMILES	OC(=O)C(=O)CBr
Target	Autophagy,Hexokinase,Apoptosis
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.98 mM);H2O:32 mg/mL (191.66 mM);DMSO:122.5 mg/mL (733.71 mM)

Bioactivity

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Target IC50	Hexokinase II:2.4 mM (Ki)

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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3Bromopyruvic acid, 3-Bromopyruvic acid, 3 Bromopyruvic acid, analogue, Apoptosis, Autophagy, Bromopyruvic acid, cells, Inhibitor, hexokinase II, Hexokinase II Inhibitor II, 3-BP, Hexokinase, MCF-7, glycolysis, inhibit, pyruvate, stress

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Compound Identifiers

PubChem CID

70684 ↗

Key Properties

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No computed properties available.

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