3-Hydroxykynurenamine

SKU: orb1741299

Description

3-Hydroxykynurenamine (3-HKA) is an anti-inflammatory tryptophan metabolite that inhibits the IFN-γ/STAT1/NF-κB pathway in dendritic cells, reducing pro-inflammatory cytokines. It demonstrates protective effects in murine models of psoriasis and immune-mediated glomerulonephritis by ameliorating disease pathology and modulating T cell responses.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	99362-47-7
MW	180.2
Formula	C₉H₁₂N₂O₂
SMILES	C(CCN)(=O)C1=C(N)C(O)=CC=C1
Target	Aryl Hydrocarbon Receptor,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

440736 ↗

Key Properties

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No computed properties available.

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