β-Anhydroicaritin

SKU: orb1300166

Description

β-Anhydroicaritin is a bioactive small molecule with demonstrated immunosuppressive effects in LPS-stimulated macrophages in vitro. Its phytosome formulation shows in vivo efficacy in ovariectomized mouse models by inhibiting bone turnover and improving bone properties without uterine stimulation, and it also protects against zymosan-induced peritonitis by modulating macrophage Ca2+ influx and iNOS expression.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	38226-86-7
MW	368.38
Purity	99.09%
Formula	C₂₁H₂₀O₆
SMILES	COc1ccc(cc1)-c1oc2c3CCC(C)(C)Oc3cc(O)c2c(=O)c1O
Target	MMP,TNF,Interleukin
Solubility	DMSO:3.69 mg/mL (10.02 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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TNF Receptor, TNFR, Tumor Necrosis Factor Receptor, β Anhydroicaritin, βAnhydroicaritin, β-Anhydroicaritin, MMP, inhibit, Matrix metalloproteinases, Inhibitor, Interleukin, Interleukin Related, b-Anhydroicaritin, Anhydroicaritin, Beta-Anhydroicaritin

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Compound Identifiers

PubChem CID

14583584 ↗

Key Properties

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No computed properties available.

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