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Anle138b

SKU: orb1220926

Description

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease.

Images & Validation

Key Properties

CAS Number882697-00-9
MW343.17
Purity>98% (HPLC)
FormulaC16H11BrN2O2?
SMILESC1OC2=C(O1)C=C(C=C2)C3=CC(=NN3)C4=CC(=CC=C4)Br
Targetothers
SolubilityDMSO:50 mg/mL (145.70 mM)

Bioactivity

In Vivo
Animal model: Two‐month‐old PLP‐hαSyn mice. Dosage: 0.6 and 2 g/kg. Administration: Oral. Result: Prevented motor deficits and neurodegeneration in the PLP‐hαSyn mice.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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2 mg
$ 70.00
5 mg
$ 100.00
10 mg
$ 160.00
25 mg
$ 320.00
50 mg
$ 460.00
100 mg
$ 670.00
200 mg
$ 960.00
500 mg
$ 1,490.00